Andrea Dossena started his international career for Italy at under-20 level. He played four times for the Italy under-20 team for around a year. Dossena was with the Italian under-20 team from 2000 to 2001. Andrea Dossena didn’t make the step up from junior level to senior level immediately. It took several years for him to make his debut for the Italian senior team after his last appearance for the junior team in 2001.

Dossenamade his first appearance for Italy during an international friendly clash with South Africa on October 17, 2007. It took six years for Andrea Dossenato make the upgrade to senior level from his last appearance at junior level.

Andrea Dossena made his second appearance for the Italian senior team as a second half substitute during the 2-2 draw with Austria on August 20, 2008. He came on just after the half-time break as Italy and Austria settled for a share of the spoils.

Dossenawent to his only major tournament with the Italian senior team at the 2009 FIFA Confederations Cup in South Africa. However, he could not prevent his team from being knocked out at the group stage. The Italians were drawn in Group B alongside Egypt, Brazil and the United States of America.

In their first game in Group B, Andrea Dossena and Italy came from behind to beat the United States 3-1. Landon Donovan gave the United States the lead from the penalty spot four minutes from the half-time break before Italy scored three times in the second half through goals from Giuseppe Rossi (brace) and Danielle De Rossi. For their second group game, Italy suffered a surprising 1-0 defeat at the hands of African team Egypt. The Italians finished third in the group with the 3-0 defeat to Brazil in their third and final group game. Andrea Dossena scored an own goal to seal the win for Brazil in the first half after Luis Fabiano had scored twice.Italy crashed out at the group stage after finishing third behind the United States and leaders Brazil. Egypt finished at the bottom of the group.